Discover the next generation of ink-based hybrid multimaterial implants.
The vision of INKplant is the combination of different biomaterials, high-resolution additive manufacturing technologies, and advanced simulation and biological evaluation, to bring a new solution for the fabrication of biomimetic implants for tissue regeneration.
INKplant addresses the complexity of regenerating different tissues in the body and has the potential to reduce healthcare costs and rehabilitation time.
Develop manufacturing technologies and materials for implants.
Create a workflow for the design optimization of 3D implants.
Demostrate the INKplant approach in four different Use Cases.
Assure the future translation of the technology to clinical application.
The implants are characterised by a Hard Phase and a Composite Phase.
The Hard Phase consists of a bi-material ceramic part and is intended to mimic the biological and mechanical performance of bone tissue.
The Composite Phase consists of a combination of biomaterials that provide the cells with the optimal environment for tissue regeneration.
Ceramic Hard Phase
Multimaterial Composite Phase
INKplant concept is based on a hybrid additive manufacturing process. The bi-material ceramic Hard Phase is fabricated by Lithographic Ceramic Manufacturing. The Composite Phase is fabricated on the surface of the ceramic parts by multimaterial Inkjet 3D Printing.
Hard Phase · By Lithoz
3D multimaterial inkjet printing
Composite Phase · By Profactor
Integrating the modelling and experimental data in a workflow that will allow the design and manufacturing of a patient-specific implant starting from medical imaging data. The manufactured implant will not only provide patient-specific dimensional fitting but also fulfill the required mechanical and biological properties to promote regeneration of the targeted tissue.
Simulation and Modelling
Characterization of 3D scaffold structures
Use case — 01 & 02.
Implants that improve symptoms and reduce joint degeneration for patients requiring partial or total meniscal resection.
The project will address the clinical need for customised treatment of osteochondral lesions in the knee.
INKplant will work to repair palatal defects caused by the common birth defect cleft palate or as a result of diseases such as cancer.
New approach for bone reconstruction when an insufficient amount of soft and hard tissue is available to place a dental implant.
Use case — 03 & 04.
Clinical Application —
INKplant works for future clinical translation during the development process, to achieve a fast market entry after finishing the project. INKplant will analyse the implications of the innovative personalised 3D implants for regenerative medicine, in order to develop ethical recommendations for INKplant Use Cases. Doctors, researchers in social humanities, and a standardization body work together to ensure the translation to a real product in the future.
Work plan —
The project is divided into 10 work packages covering the scientific and technical aspects of INKplant, social humanities and cross-cutting priorities, exploitation and dissemination of results, and project management.
WP01 · Led by PRO
Led by Profactor
Materials & manufacturing
Design & characterization
WP02 · Led by MUW
Led by Medical University Vienna
Definition of requirements
WP10 · Led by BMC
Led by BioMed Center Innovation
Exploitation & Dissemination