Universitätsmedizin Berlin


Michael Sittinger

PhD. - Scientific Manager

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The Charité Tissue Engineering team pioneered 3D cell-based tissue regeneration

Transforming discoveries of biomaterials engineering into novel approaches for personalized regenerative treatments

The Charité - Universitätsmedizin Berlin has a 300-year history of excellence in world-class medicine and research. It is from this tradition that the Charité derives its historical mission and societal responsibility in terms of promoting outstanding medical research and providing forward-looking medical teaching and innovative healthcare, both nationally and internationally. It employs over 17.000 people, including 5.000 scientists and doctors, 5.000 nurses, and caregivers. It’s one of Berlin’s largest employers.

Charité Tissue Engineering will be carrying out the required biomedical research for INKplant and will focus on transforming discoveries of biomaterials engineering into novel approaches for personalized regenerative treatments, as well as to generate new research approaches from clinical observations.

On a global scale, the Charité Tissue Engineering Team is one of the very first pioneers in the field of tissue engineering. The Lab was established in 1994 for multidisciplinary applied research on cell culture, biomaterials and tissue growth factors. Since then, the team has developed pioneering 3D cell-based and matrix products for articular cartilage and bone regeneration and is strongly committed to a translational mindset to bring research results from bench to bedside and from bench to market.

The Tissue Engineering Lab is located in the Department of Rheumatology and Clinical Immunology, it is particularly interested in regenerative therapeutics for joint diseases. This group designed and published in vitro models for rheumatoid arthritis and osteoarthritis based on engineered tissues in order to research aspects that influence homeostasis and joint tissue degeneration. The team intensively worked with mesenchymal stromal cells and has thoroughly explored their role and possible application in tissue regeneration.

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